Background Identification of futile recanalisation following endovascular therapy (EVT) in patients with acute ischaemic stroke is both crucial and challenging.Here, we present a novel risk stratification system based on hybrid machine learning method for predicting futile recanalisation.Methods Hybrid machine learning models were developed to addr

Positive allosteric modulators (PAMs) of the GABAB receptor (GABAB PAMs) are of interest in the addiction field due to their ability to suppress several behaviors motivated by drugs of abuse.KK-92A is a novel GABAB PAM found to attenuate intravenous self-administration of nicotine and reinstatement of nicotine seeking in rats.This present study was

The use of corrugated board packaging is very popular in most industry sectors, but the food industry is one of the main consumers.Special requirements are placed on corrugated board in the food industry since the level of humidity necessary may be as high as 85-90% rH and this can greatly influence on the performance of the packaging.This influenc

In recent years, the number of incidents involving aqueduct damage due to vehicle impact has steadily increased, significantly affecting the safe operation igloo white operation of water transfer projects.To investigate the dynamic response characteristics of aqueduct structures under vehicle impact, a numerical model of vehicle impact on an aquedu

Asmatullah Kakar,1 Yosra Mouelhi,1 Anderson Loundou,1 Adeline Crémades,1 Stephanie Gentile1,2 1Aix Marseille University School of Medicine — La Timone Medical Campus, EA 3279: CEReSS — Health Service Research and Quality of Life Center, Marseille, France; 2Assistance Publique, Hôpitaux de Marseille (AP-HM), Marseille, Franc